Phenylcarbamic acid esters
Medchemexpress LLC 4-(4-Boc-piperazinemethyl)phenylboronic acid pinacol ester | 470478-90-1 | 98.5% | C21H33BN2O4 | 100 G
4-(4-Boc-piperazinemethyl)phenylboronic acid pinacol ester is a PROTAC linker utilized in the synthesis of CST905. This compound functions as part of Proteolysis Targeting Chimeras (PROTACs), which are molecules designed to selectively degrade target proteins by harnessing the intracellular ubiquitin-proteasome system. PROTACs achieve this by using two ligands connected by a linker: one binds to an E3 ubiquitin ligase, and the other targets a specific protein. This product is for research use only.
- Functions as a PROTAC linker
- Used in the synthesis of CST905
- Exploits the intracellular ubiquitin-proteasome system
- Designed for selective degradation of target proteins
- Purity is 98.50%
- Molecular weight is 388.31
- Appearance is solid, white to light yellow
Medchemexpress LLC (4S)-1-Boc-4-fluoro-D-proline | 681128-50-7 | 97.0% | 233.24 g·mol⁻¹ | C10H16FNO4 | 25 G
(4S)-1-Boc-4-fluoro-D-proline is a Boc-protected, fluoro-substituted D-proline derivative used as a synthetic building block in organic and medicinal chemistry. It supplies a stereodefined fluorinated proline residue for incorporation into peptides and small molecules, enabling conformation control and exploration of structure-activity relationships.
- Boc-protected amino acid compatible with standard peptide coupling chemistry.
- Fluorine substitution at the 4-position to influence conformational preference and metabolic stability.
- D-configuration (4S) provides stereochemical control for peptide design.
- High chemical purity suitable for synthesis applications.
- Available in gram-scale quantities for preparative synthesis.
Medchemexpress LLC Ccr2 protein, mouse (N-His, C-Myc) | 93.0% | 100UG
Recombinant CCR2 protein (mouse) representing amino acids M1-A55, expressed in Escherichia coli and supplied with an N-terminal 10xHis tag and a C-terminal c-Myc tag. The preparation has an apparent molecular weight of ~16 kDa and purity greater than 90% by reducing SDS-PAGE. It is intended for in vitro biochemical and binding studies involving CCR2 and its ligands. Store lyophilized or frozen, and aliquot to avoid freeze-thaw.
- Recombinant fragment corresponding to CCR2 (mouse)
- N-terminal 10xHis and C-terminal c-Myc tags for detection and purification
- Expressed in Escherichia coli for high-yield production
- Approximate molecular weight 16 kDa
- Purity greater than 90% as determined by reducing SDS-PAGE
- Suitable for biochemical and binding assays
- Stable when stored at -20°C or -80°C; aliquot to avoid freeze-thaw
Medchemexpress LLC COMMD8 Human N-His 50ug | 50ug
COMMD8 Protein Human (N-His) expresses in E coli with a His tag at the N-terminus COMMD8 is a protein that binds to the C-terminal amino acid sequence (residues 306 352) of human CXCR4[1]
Medchemexpress LLC N-Boc-Tris | 146651-71-0 | ≥97.0% | C9H19NO5 | 100 G
N-Boc-Tris is a protective reagent that utilizes the Boc protecting group to protect amino groups in organic synthesis and pharmaceutical research and development, thereby avoiding unnecessary side reactions. It is a white to off-white solid with a purity of ≥97.0%.
Medchemexpress LLC Propanoic acid, 3,3'-[(2-amino-1,3-propanediyl)bis(oxy)]bis-, 1,1'-bis(1,1-dimethylethyl) ester | 2171072-53-8 | 99.7% | C17H33NO6 | 250 MG
NH-bis(C1-PEG1-Boc) is an alkyl/ether-based PROTAC linker used in the synthesis of PROTACs. This compound is a key component in creating PROTACs, which are molecules designed to selectively degrade target proteins within a cell.
- Alkyl/ether-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
Medchemexpress LLC 4,7,10,13-Tetraoxahexadecanedioic acid, 1-(1,1-dimethylethyl) ester | 1835759-85-7 | 98.3% | 350.40 | 25 MG
Acid-PEG4-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker utilized in the synthesis of PROTACs for the inhibition of mTOR. This product is intended for research use only.
- PEG- and Alkyl/ether-based linker
- Used in the synthesis of PROTACs
- Inhibits mTOR
- Intended for research use only
- Utilizes the intracellular ubiquitin-proteasome system for selective degradation of target proteins
Medchemexpress LLC N-β-alanyldopamine hydrochloride | 58077-93-3 | >99.9% | 260.72 | 1 ML
N-β-alanyldopamine hydrochloride (NBAD hydrochloride) is recognized as the primary dopamine derivative found in haemolymph and is intended exclusively for research applications.
- Primary dopamine derivative in haemolymph
- For research use only
Medchemexpress LLC Boc-NH-PEG7-acid | 2055044-68-1 | C22H43NO11 | 100 MG
Boc-NH-PEG7-acid is a polyethylene glycol (PEG)-based PROTAC linker. This compound is primarily used in the synthesis of PROTACs, which are designed to selectively degrade target proteins by exploiting the intracellular ubiquitin-proteasome system.
- Used as a PROTAC linker
- PROTACs contain two ligands connected by a linker
- Ligands bind to an E3 ubiquitin ligase and a target protein
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Bloc1s2 recombinant human protein (N-terminal GST tagged) | 97.0% | 5 UG
Recombinant human BLOC1S2 protein with an N-terminal GST tag supplied as a 5 μg aliquot for research use. The protein is expressed in Escherichia coli and provided as a purified preparation suitable for molecular biology and biochemical assays, including antibody validation and electrophoresis applications.
- N-terminal GST tag for purification and detection.
- Expressed in E. coli for efficient production.
- Purity approximately 97.0% by vendor analysis.
- Suitable for SDS-PAGE, western blot, and antibody generation.
- Approximate molecular weight 34 kDa.
Medchemexpress LLC Gstm2 protein, human (his, solution) | >95.0% | 5 UG
Recombinant human glutathione S-transferase Mu 2 (GSTM2) with an N-terminal 6xHis tag, expressed in Escherichia coli and supplied lyophilized from a Tris-based buffer. The protein is approximately 26 kDa and >95% pure by reducing SDS-PAGE, and is intended for use in biochemical assays, structural studies, and antibody validation.
- N-terminal 6xHis tag for affinity purification and detection.
- Expressed in Escherichia coli for high yield production.
- Lyophilized formulation for extended stability and storage.
- Purity greater than 95% as assessed by reducing SDS-PAGE.
- Approximate molecular weight of 26 kDa.
- Suitable for biochemical assays and antibody validation.